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What will be the X factor for CFS?

How did I few months ago, here's another article published in category Wall Street Journal Health Blog , Katherine Hobson, the saga XMRV. The article is on November 4.

E 'for over a year that researchers have found XMRV retrovirus in the blood of patients with chronic fatigue syndrome. Now people are asking: what's next for the X?

The debate about the truth of the link between XMRV and CFS and other diseases is still lively, mainly because some groups have found the virus in the blood of high proportion of people with the disease, while others have failed to find in any patient.

An article published yesterday (November 3, ed) Viruses in the paper, provides guidelines for researchers to study the link between XMRV and CFS. All agree that reaching a consensus on standards to be applied in these studies is critical.

The article was written by someone who knows what it takes to find XMRV - Ila Singh, a scientist at the University of Utah who has published an article on the discovery XMRV in patients with cancer prostate. He is now working on una serie di studi sull’XMRV.

Tra i suggerimenti della Singh: Gli studi devono includere un grande numero di pazienti, tutti diagnosticati secondo criteri ben stabiliti per la CFS. Anche il numero di persone sane utilizzati negli studi come gruppo di controllo dovrebbe essere alto e dovrebbero provenire dalla stessa zona geografica dei pazienti. Il sangue dei pazienti e quello dei controlli sani deve essere raccolto e analizzato allo stesso modo. I ricercatori non dovrebbero sapere a quale gruppo appartiene il sangue che stanno studiando, e bisognerebbe utilizzare più di un metodo per rilevare la presenza dell’XMRV.

Singh aggiunge che la ricerca “ideale” should also use at least one method that has already been successful to detect the virus in previously published studies, also using the same blood samples.

Kim McCleary, president of the CFIDS Association of America, a group representing the CFS, said that Singh's article offers "a strong framework for reducing some of the conflicting issues in the research that has already been published."

The guidelines are timely. W. Ian Lipkin, a virus hunter at Columbia University appointed by the government to resolve the issues sull'XMRV, convened a meeting this week. Representatives del SSN Americano e le associazioni si trovano a New York per sviluppare una strategia per uno studio che vuole determinare se l’XMRV sia prevalente nei pazienti con la CFS.

Singh dice al Health Blog: “Ho inviato una copia dell’articolo ad Ian”.

Dunque la saga continua per trovare il famoso X factor e pare che in America siano proprio decisi a trovarlo....Qualcuno qui si è svegliato o vogliamo tutti stare a guardare? Scienziati italiani in ascolto: Datevi una mossa!!